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High-Protein Spinach and Artichoke Chicken Casserole

A creamy, cheesy, low-carb casserole featuring tender chicken, wilted spinach, and artichokes in a high-protein Greek yogurt and parmesan sauce.
Print Recipe
Prep Time 15 minutes
Cook Time 25 minutes
Total Time 40 minutes
Servings: 6 servings
Course: Dinner, Main Course
Cuisine: American, Keto
Calories: 380
Ingredients Equipment Method Notes

Ingredients
  

Chicken & Veggies
  • 1.5 lbs chicken breast cubed into 1-inch pieces
  • 10 oz spinach fresh or frozen (thawed/squeezed dry)
  • 14 oz artichoke hearts canned, drained and quartered
  • 2 tbsp olive oil divided
  • 4 cloves garlic minced
Creamy Sauce
  • 4 oz cream cheese softened
  • 0.5 cup Greek yogurt plain, non-fat or low-fat
  • 0.25 cup chicken broth
  • 0.5 cup parmesan cheese grated
  • 1 cup mozzarella cheese shredded
  • 0.5 tsp red pepper flakes optional
  • 1 tsp salt to taste
  • 0.5 tsp black pepper

Equipment

  • Large Skillet
  • 9x13 Baking Dish
  • Chef's Knife
  • Cutting board

Method
 

  1. Preheat oven to 375°F (190°C). Lightly grease a 9x13 inch baking dish.
  2. Heat 1 tbsp olive oil in a large skillet over medium-high heat. Season chicken cubes with salt and pepper, then sear for 3-4 minutes until browned (not fully cooked). Remove chicken and set aside.
  3. In the same skillet, add remaining 1 tbsp olive oil and minced garlic. Sauté for 30 seconds until fragrant.
  4. Add spinach and cook until wilted (2-3 mins). If using frozen spinach, ensure it is squeezed dry first.
  5. Reduce heat to low. Stir in cream cheese, Greek yogurt, parmesan cheese, and chicken broth. Stir constantly until smooth and creamy.
  6. Return chicken to the pan and add drained artichoke hearts. Toss to coat everything in the sauce.
  7. Transfer the mixture to the prepared baking dish. Top evenly with shredded mozzarella cheese.
  8. Bake for 20-25 minutes until bubbly and cheese is melted. Broil for the last 2 minutes for a golden crust.

Notes

Ensure spinach is very dry to prevent a watery sauce. Serve with a side salad or cauliflower rice.